Chemical Production from Methanol Using Natural and Synthetic Methylotrophs
| Autor: | Arvin Y. Chen, Ethan I. Lan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_element
Raw material Applied Microbiology and Biotechnology Chemical production Metabolic engineering chemistry.chemical_compound Synthetic biology Natural gas Methylobacterium extorquens Amino Acids Biological Products business.industry Methanol General Medicine Carbon Dioxide Metabolic Engineering chemistry Saccharomycetales Carbon dioxide Molecular Medicine Synthetic Biology Biochemical engineering business Carbon Metabolic Networks and Pathways |
| Zdroj: | Biotechnology Journal. 15:1900356 |
| ISSN: | 1860-7314 1860-6768 |
| DOI: | 10.1002/biot.201900356 |
| Popis: | Methanol as a chemical feedstock is becoming increasingly important as it is derived from natural gas and is a feasible end-product for captured carbon dioxide. Biological conversion of methanol through natural and synthetic methylotrophs increases the chemical repertoire and is an important direction for one carbon (C1) based chemical economy. Advances in the metabolic engineering and synthetic biology enable development of microbial cell factories for converting methanol into various platform chemicals. In this review, the current status of methanol utilizing microbial factory development is summarized. Also the development of synthetic methylotrophy and methanol-augmented bioproductions is discussed. |
| Databáze: | OpenAIRE |
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