Epidemiologic surveillance of multidrug-resistant bacteria in a teaching hospital: A 3-year experience
| Autor: | Silvia Maria dos Santos Saalfeld, Cecília Saori Mitsugui, Sheila Alexandra Belini Nishiyama, Cesar Helbel, Bruno Buranello Costa, M.N. Zarpellon, Elisabeth Eyko Aoki, Maria Cristina Bronharo Tognim, Giselle Fukita Viana, Nathalie Kira Tamura |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Isolation (health care) Epidemiology 030106 microbiology Prevalence Drug resistance Microbial Sensitivity Tests 030501 epidemiology 03 medical and health sciences Internal medicine Drug Resistance Multiple Bacterial medicine Humans Terminal cleaning Hospitals Teaching Phylogeny Infection Control biology Bacteria business.industry Health Policy Incidence (epidemiology) Public Health Environmental and Occupational Health Epidemiologic Surveillance biology.organism_classification Acinetobacter baumannii Anti-Bacterial Agents Bacterial Typing Techniques Infectious Diseases Enterococcus Epidemiological Monitoring 0305 other medical science business |
| Zdroj: | American journal of infection control. 46(4) |
| ISSN: | 1527-3296 |
| Popis: | Background The objective of this prospective study was to verify the effectiveness of a multidisciplinary surveillance program that was implemented in a teaching hospital in southern Brazil, to prevent and control the spread of multidrug-resistant organisms. Methods The program implemented involved establishment of prevention guidelines, hand-hygiene promotion, isolation of patients colonized or infected by such organisms, enforced contact precautions, and terminal cleaning and disinfection of isolation rooms. A microbiology service, previously provided by an external laboratory, was established in the hospital. Detection of bacteria-resistant genes and molecular typing were performed also. Results Statistically significant differences were observed between the pre- and post-intervention periods (P = .00198). Control measures were effective in blocking the dissemination of a previously endemic clone of Acinetobacter baumannii. Changes were observed in the dissemination pattern, from a monoclonal to a polyclonal mode. The incidence of vancomycin-resistant Enterococcus during the surveillance period was low. Only 2 isolates of BLAKPC-positive Klebsiella pneumoniae (distinct profiles), and 5 isolates of BLASPM-positive Pseudomonas aeruginosa (a single cluster), were detected. Conclusions These results indicate that the surveillance program implemented was effective in preventing the spread of multidrug-resistant organisms in the hospital. |
| Databáze: | OpenAIRE |
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