A Case Report of Cardiogenic Syncope Due to Loperamide Abuse: Acute Presentation and Novel Use of Buprenorphine
| Autor: | James A. Chenoweth, Angela F. Jarman, David J Betting |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Cardiogenic syncope
Loperamide Case Report Emergency Nursing 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine High doses Medicine 030212 general & internal medicine dysrhythmia Sodium bicarbonate Conduction abnormalities business.industry RC86-88.9 030208 emergency & critical care medicine Opioid use disorder Medical emergencies. Critical care. Intensive care. First aid medicine.disease buprenorphine Opioid chemistry Anesthesia syncope Emergency Medicine business Buprenorphine medicine.drug |
| Zdroj: | Clinical Practice and Cases in Emergency Medicine, Vol 5, Iss 2 (2021) Clinical Practice and Cases in Emergency Medicine |
| Popis: | Author(s): Betting, David J.; Chenoweth, James A.; Jarman, Angela F. | Abstract: Introduction: Loperamide is a non-prescription anti-diarrheal agent targeting µ-opioid receptors in the intestinal tract. At high doses it crosses the blood-brain barrier, where µ-opioid agonism can cause euphoric effects. Misuse has been increasing for both the euphoric effects and as an alternative treatment for opioid dependence and withdrawal.Case Report: Here we report the case of a 30-year-old woman presenting with syncope, who was found to have severe myocardial conduction delays in the setting of chronic loperamide abuse.Conclusion: Treatment with sodium bicarbonate and hypertonic sodium resulted in improvement of her conduction abnormalities. Prior to discharge she was initiated on buprenorphine for her opioid use disorder. |
| Databáze: | OpenAIRE |
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