Enantioselective synthesis of α-amino ketones through palladium-catalyzed asymmetric arylation of α-keto imines
| Autor: | Wei Wen, Zhao-Pin Ai, Chang-Lin Yang, Chao-Xing Li, Zhu-Lian Wu, Tian Cai, Qi-Xiang Guo |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Chemical Science. 13:3796-3802 |
| ISSN: | 2041-6539 2041-6520 |
| DOI: | 10.1039/d2sc00386d |
| Popis: | Chiral α-amino ketones are common structural motifs in natural products and pharmaceuticals, as well as important synthons in organic synthesis. Thus, establishing efficient methods for preparing compounds with these privileged scaffolds is an important endeavor in synthetic chemistry. Herein we disclose a new catalytic asymmetric approach for the synthesis of chiral α-amino ketones through a chiral palladium-catalyzed arylation reaction of |
| Databáze: | OpenAIRE |
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