Eligibility for reperfusion therapy and outcome in elderly patients with acute myocardial infarction
| Autor: | Aumont Mc, Dominique Himbert, Jean-Michel Juliard, Gourgon R, Phillippe Gabriel Steg, Neukirch F |
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| Rok vydání: | 1994 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Myocardial Infarction Primary angioplasty Myocardial Reperfusion QT interval Reperfusion therapy Angioplasty Internal medicine medicine Humans Thrombolytic Therapy Myocardial infarction Aged Retrospective Studies Chemotherapy business.industry Contraindications Age Factors Thrombolysis medicine.disease Coronary heart disease Surgery Survival Rate Treatment Outcome Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | European Heart Journal. 15:483-488 |
| ISSN: | 1522-9645 0195-668X |
| DOI: | 10.1093/oxfordjournals.eurheartj.a060531 |
| Popis: | Reperfusion therapy by thrombolysis or angioplasty was considered in 260 unselected patients consecutively admitted within 6 h of the onset of Q wave myocardial infarction. Rates of reperfusion and in-hospital mortality were compared in 206 patients70 years and 54 patientsor = 70 years. Early reperfusion was obtained in 86.4% of the patients under 70 years and in 72.2% of those over 70 (P0.01). Thrombolysis was more frequently used in the younger group (66.0% vs 31.5%, P10(-5)), and primary angioplasty in the older (44.4% vs 29.6%, P0.05). Overall in-hospital mortality was higher in the older group (22.2% vs 4.4%, P10(-5)). After successful reperfusion, mortality was 12.8% in the patients over 70 and 3.9% in those under 70. After failed or unproven reperfusion, mortality was 46.7% in the patients over 70 and 7.1% in those under 70. Reperfusion therapy is feasible in the majority of patients over 70 years, but failure to attempt or to achieve reperfusion is associated with a poor outcome. Although not controlled, this study provides an incentive for attempting early reperfusion therapy as often as possible in the elderly with acute myocardial infarction. |
| Databáze: | OpenAIRE |
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