Prevalence, predictors, and outcomes of patient prosthesis mismatch in women undergoing TAVI for severe aortic stenosis: Insights from the WIN-TAVI registry

Autor: Piera Capranzano, Jaya Chandrasekhar, Neil Ruparelia, Petros Nihoyannopoulos, Maria Cruz Ferrer-Gracia, Alessandro Iadanza, Vasileios F. Panoulas, Ghada W. Mikhail, Julinda Mehilli, Christoph Naber, Nicolas Dumonteil, Iqbal S. Malik, Nicolas M. Van Mieghem, Clayton Snyder, Anna Sonia Petronio, Samantha Sartori, Gherardo Busi, Gennaro Sardella, Daniela Trabattoni, Emanuele Meliga, Marie Claude Morice, Zhongjie Zhang, Nilesh Sutaria, Didier Tchetche, Sayan Sen, Patrizia Presbitero, Chiara Fraccaro, Roxana Mehran, Samin K. Sharma, Peter C. Kievit, Thierre Lefèvre, Alaide Chieffo
Přispěvatelé: Cardiology
Jazyk: angličtina
Rok vydání: 2021
Předmět:
medicine.medical_specialty
Time Factors
Transcatheter aortic
medicine.medical_treatment
Population
030204 cardiovascular system & hematology
outcomes
patient-prosthesis mismatch
Prosthesis
TAVI
Transcatheter Aortic Valve Replacement
03 medical and health sciences
0302 clinical medicine
Postoperative Complications
Aortic valve replacement
SDG 3 - Good Health and Well-being
Risk Factors
Internal medicine
Female patient
medicine
Prevalence
Humans
Radiology
Nuclear Medicine and imaging
females
030212 general & internal medicine
Registries
education
Heart Valve Prosthesis Implantation
education.field_of_study
business.industry
Incidence (epidemiology)
General Medicine
Aortic Valve Stenosis
medicine.disease
Stenosis
Treatment Outcome
Aortic Valve
Heart Valve Prosthesis
Cardiology
Female
Cardiology and Cardiovascular Medicine
business
Lower mortality
Zdroj: Catheterization and Cardiovascular Interventions, 97(3), 516-526. Wiley-Liss Inc.
ISSN: 1522-1946
Popis: Objective: To evaluate the incidence, predictors and outcomes of female patients with patient-prosthesis mismatch (PPM) following transcatheter aortic valve intervention (TAVI) for severe aortic stenosis (AS). Background: Female AS TAVI recipients have a significantly lower mortality than surgical aortic valve replacement (SAVR) recipients, which could be attributed to the potentially lower PPM rates. TAVI has been associated with lower rates of PPM compared to SAVR. PPM in females post TAVI has not been investigated to date. Methods: The WIN-TAVI (Women's INternational Transcatheter Aortic Valve Implantation) registry is a multicenter registry of women undergoing TAVR for severe symptomatic AS. Two hundred and fifty patients with detailed periprocedural and follow-up echocardiographic investigations were included in the WIN-TAVI echocardiographic sub-study. PPM was defined as per European guidelines stratified by the presence of obesity. Results: The incidence of PPM in our population was 32.8%. Patients with PPM had significantly higher BMI (27.4 ± 6.1 vs. 25.2 ± 5.0, p =.002), smaller sized valves implanted (percentage of TAVI ≤23 mm 61% vs. 29.2%, PPM vs. no PPM, p Conclusions: PPM in females undergoing TAVI occurs in one third of patients. BMI and valve size ≤23 mm are independent predictors. Larger registries are required to determine the impact of PPM on future clinical outcomes.
Databáze: OpenAIRE
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