Efficacy of hippocampal transection for left temporal lobe epilepsy without hippocampal atrophy
| Autor: | Taro Kusakabe, Shigeki Sunaga, Michiharu Morino, Hiroyuki Shimizu, Hidenori Sugano |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Neurosurgery Hippocampus Hippocampal formation Electroencephalography Behavioral Neuroscience Epilepsy Iodine Isotopes medicine Humans Ictal Tomography Emission-Computed Single-Photon medicine.diagnostic_test Iofetamine medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Epilepsy Temporal Lobe Neurology Scalp Anesthesia Wada test Female Neurology (clinical) Verbal memory Psychology |
| Zdroj: | Epilepsy & Behavior. 21:94-99 |
| ISSN: | 1525-5050 |
| Popis: | We describe a case of left temporal lobe epilepsy without hippocampal atrophy. A 31-year-old woman presented with typical symptoms of complex partial seizures. Magnetic resonance imaging demonstrated slightly obscure internal structures in the left hippocampus. Scalp electroencephalography revealed interictal epileptiform discharges in the left temporal lobe. A Wada test with propofol determined the language-dominant hemisphere to be the left. Intraoperative electrocorticography revealed active epileptic discharges in the hippocampus and the anterior temporal basal area. The hippocampal epileptic area was treated with multiple transection, which led to the complete cessation of epileptic discharges. After surgery, the Rey Auditory Verbal Learning Test score decreased from 12 to 9. However, it returned to the preoperative level 6 months after surgery. We describe this case as a typical example demonstrating the efficacy of hippocampal transection for seizure control and the preservation of verbal memory. |
| Databáze: | OpenAIRE |
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