Seasonality in clinical courses of Kawasaki disease
| Autor: | Kenichiro Yamaguchi, Yasufumi Hidaka, Yoshihisa Fujino, Yoshie Tomita, Koichi Kusuhara, Junji Kamizono, Takayuki Hoshina, Daisuke Shimizu, Jun Muneuchi, Masumi Kojiro, Masaru Kawamura |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Coronary artery abnormality Mucocutaneous Lymph Node Syndrome 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Japan Internal medicine medicine Humans Immunologic Factors Child IVIG Therapy Retrospective Studies business.industry Infant Newborn Clinical course Immunoglobulins Intravenous Infant Seasonality medicine.disease Treatment Outcome Child Preschool 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Female Kawasaki disease Seasons Cold period business |
| Zdroj: | Archives of Disease in Childhood. 104:694-696 |
| ISSN: | 1468-2044 0003-9888 |
| DOI: | 10.1136/archdischild-2018-315267 |
| Popis: | ObjectiveEpidemics of Kawasaki disease (KD) are well known; however, the seasonal variation in the clinical course of KD is uncertain. The aim of this study was to investigate the seasonality in the clinical course of KD.MethodsThis study included 744 patients who were admitted to six hospitals in Kitakyushu City for KD from 2010 to 2014. We divided the patients into two groups according to the average monthly temperature (warm and cold periods) and compared the clinical courses of KD.ResultsThe clinical courses of 715 patients who were initially treated with intravenous immunoglobulin (IVIG) were investigated. The proportion of patients with resistance to the initial IVIG therapy was significantly higher during the warm period than during the cold period (p=0.016). There was no seasonality in the proportion of patients with coronary artery abnormalities.ConclusionSeasonality was observed in the response to IVIG therapy of patients with KD. |
| Databáze: | OpenAIRE |
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