Breast Cancer Preoperative Staging: Does Contrast-Enhanced Magnetic Resonance Mammography Modify Surgery?
| Autor: | F. Genta, Davide Brizzi, Eugenio Zanon, Francesco Deltetto, Chiara Perono Biacchiardi, Marco Camanni |
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| Rok vydání: | 2011 |
| Předmět: |
Cancer Research
medicine.medical_specialty Article Subject integumentary system medicine.diagnostic_test business.industry medicine.medical_treatment Lumpectomy Ultrasound lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease lcsh:RC254-282 Surgical planning Surgery Magnetic resonance mammography Breast cancer Oncology Biopsy Clinical Study Medicine Mammography Pharmacology (medical) business Mastectomy |
| Zdroj: | International Journal of Breast Cancer International Journal of Breast Cancer, Vol 2011 (2011) |
| ISSN: | 2090-3189 |
| DOI: | 10.4061/2011/757234 |
| Popis: | Women with newly diagnosed breast cancer may have lesions undetected by conventional imaging. Recently contrast-enhanced magnetic resonance mammography (CE-MRM) showed higher sensitivity in breast lesions detection. The present analysis was aimed at evaluating the benefit of preoperative CE-MRM in the surgical planning. From 2005 to 2009, 525 consecutive women (25–75 years) with breast cancer, newly diagnosed by mammography, ultrasound, and needle-biopsy, underwent CE-MRM. The median invasive tumour size was 19 mm. In 144 patients, CE-MRM identified additional lesions. After secondlook, 119 patients underwent additional biopsy. CE-MRM altered surgery in 118 patients: 57 received double lumpectomy or wider excision (41 beneficial), 41 required mastectomy (40 beneficial), and 20 underwent contra lateral surgery (18 beneficial). The overall false-positive rate was 27.1% (39/144). CE-MRM contributed significantly to the management of breast cancer, suggesting more extensive disease in 144/525 (27.4%) patients and changing the surgical plan in 118/525 (22.5%) patients (99/525, 18.8% beneficial). |
| Databáze: | OpenAIRE |
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