Isonatric Dialysis Biofeedback in Hemodiafiltration with Online Regeneration of Ultrafiltrate in Hypertensive Hemodialysis Patients
| Autor: | Olivier Mat, Jean-Claude Stolear, Lucile Mercadal, Dominique Vandervelde, Yahsou Delmas, Christine Fumeron, Angelo Testa, Christian Tielemans, I. Simon, Lise Mandart, Frédéric Debelle, Sophie Tezenas du Montcel, Louise Chevalier |
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| Přispěvatelé: | Clinical sciences |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment 030232 urology & nephrology Diastole Blood Pressure Hemodiafiltration 030204 cardiovascular system & hematology Biofeedback law.invention Hemodialysis Solutions 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Internal medicine Hfr cell medicine Humans Dialysis Antihypertensive Agents Aged Monitoring Physiologic Aged 80 and over business.industry Sodium Hematology General Medicine Middle Aged biochemical phenomena metabolism and nutrition equipment and supplies Surgery carbohydrates (lipids) Blood pressure Nephrology Hypertension Cardiology Fluid Therapy bacteria Female Kidney Diseases Hemodialysis Hypotension business |
| Popis: | Dialysis biofeedback in hemodiafiltration with online regeneration of ultrafiltrate (HFR) could help to improve arterial hypertension. We evaluated the impact of isonatric HFR (HFR-iso) on hypertension control compared to conventional HFR. Forty-seven hemodialysis patients were included and randomized (ratio 2/1) HFR-iso versus HFR during 24 dialysis sessions. In the HFR-iso group (32 patients, 768 dialysis sessions), the predialytic systolic blood pressure (BP) decreased from S1 to S24 of 9 ± 20 mm Hg and increased of 5 ± 24 mm Hg in the HFR group (15 patients, 360 dialysis sessions), variation that differed between the 2 groups (ΔS1-S24, p = 0.035; interaction group*time, p = 0.012). The diastolic BP (HFR-iso -3 ± 14 mm Hg vs. HFR 5 ± 13 mm Hg; p = 0.088), the DDD of antihypertensive treatment and the dry weight did not vary significantly during the study. Number of sessions complicated by symptomatic hypotension was similar in the 2 groups. HFR-iso improved BP control without increasing dialysis hypotension episodes. Short Summary: In this multicenter, open-label, controlled, randomized study, we evaluated the impact of dialysis biofeedback in HFR on arterial hypertension compared to conventional HFR. We observed that HFR-iso improved arterial BP control without increasing dialysis hypotension episodes. |
| Databáze: | OpenAIRE |
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