Validation of aortic valve 4D flow analysis and myocardial deformation by cardiovascular magnetic resonance in patients after the arterial switch operation

Autor: J.J.M. Westenberg, Mieke M. P. Driessen, Heynric B. Grotenhuis, Bart W. Driesen, Johannes M.P.J. Breur, Pieter A. Doevendans, Folkert J. Meijboom, E. C. de Baat, W. H. S. van Wijk, Tim Leiner
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Aortic valve
Male
lcsh:Diseases of the circulatory (Cardiovascular) system
Transposition of Great Vessels
Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]
Left
Arterial switch operation
4D flow
Hemodynamics
Magnetic Resonance Imaging
Cine/methods
Heart Ventricles/diagnostic imaging
Ventricular Function
Left
030218 nuclear medicine & medical imaging
Ventricular Dysfunction
Left
0302 clinical medicine
Aortic Valve Insufficiency/diagnostic imaging
Mitral valve
Ventricular Dysfunction
Ventricular Function
Prospective Studies
CMR
TGA
Radiological and Ultrasound Technology
medicine.diagnostic_test
Myocardial Perfusion Imaging
Stroke volume
Magnetic Resonance Imaging
Myocardial Perfusion Imaging/methods
medicine.anatomical_structure
Transposition of Great Vessels/surgery
Treatment Outcome
Great arteries
Echocardiography
Aortic Valve
Predictive value of tests
Cardiology
Female
Left/diagnostic imaging
Cardiology and Cardiovascular Medicine
Ventricular Dysfunction
Left/diagnostic imaging
Blood Flow Velocity
Adult
medicine.medical_specialty
Adolescent
Heart Ventricles
Aortic Valve Insufficiency
Magnetic Resonance Imaging
Cine
Cine/methods
03 medical and health sciences
Young Adult
Arterial Switch Operation/adverse effects
Predictive Value of Tests
Internal medicine
medicine
Journal Article
Humans
Radiology
Nuclear Medicine and imaging
Comparative Study
Validation Studies
Angiology
business.industry
Research
Reproducibility of Results
Magnetic resonance imaging
Feature tracking
Aortic Valve/diagnostic imaging
Cross-Sectional Studies
lcsh:RC666-701
business
Zdroj: Journal of Cardiovascular Magnetic Resonance, Vol 21, Iss 1, Pp 1-10 (2019)
Journal of Cardiovascular Magnetic Resonance, 21, 20
Journal of Cardiovascular Magnetic Resonance, 21, 1, pp. 20
Journal of Cardiovascular Magnetic Resonance
Journal of Cardiovascular Magnetic Resonance, 21(1). BioMed Central
Journal of Cardiovascular Magnetic Resonance, 21. BMC
ISSN: 1097-6647
Popis: Contains fulltext : 215340.pdf (Publisher’s version ) (Open Access) BACKGROUND: Aortic regurgitation (AR) and subclinical left ventricular (LV) dysfunction expressed by myocardial deformation imaging are common in patients with transposition of the great arteries after the arterial switch operation (ASO). Echocardiographic evaluation is often hampered by reduced acoustic window settings. Cardiovascular magnetic resonance (CMR) imaging provides a robust alternative as it allows for comprehensive assessment of degree of AR and LV function. The purpose of this study is to validate CMR based 4-dimensional flow quantification (4D flow) for degree of AR and feature tracking strain measurements for LV deformation assessment in ASO patients. METHODS: A total of 81 ASO patients (median 20.6 years, IQR 13.5-28.4) underwent CMR for 4D and 2D flow analysis. CMR global longitudinal strain (GLS) feature tracking was compared to echocardiographic (echo) speckle tracking. Agreements between and within tests were expressed as intra-class correlation coefficients (ICC). RESULTS: Eleven ASO patients (13.6%) showed AR > 5% by 4D flow, with good correlation to 2D flow assessment (ICC = 0.85). 4D flow stroke volume of the aortic valve demonstrated good agreement to 2D stroke volume over the mitral valve (internal validation, ICC = 0.85) and multi-slice planimetric LV stroke volume (external validation, ICC = 0.95). 2D flow stroke volume showed slightly less, though still good agreement with 4D flow (ICC = 0.78) and planimetric LV stroke volume (ICC = 0.87). GLS by CMR was normal (- 18.8 +/- 4.4%) and demonstrated good agreement with GLS and segmental analysis by echocardiographic speckle tracking (GLS = - 17.3 +/- 3.1%, ICC of 0.80). CONCLUSIONS: Aortic 4D flow and CMR feature tracking GLS analysis demonstrate good to excellent agreement with 2D flow assessment and echocardiographic speckle tracking, respectively, and can therefore reliably be used for an integrated and comprehensive CMR analysis of aortic valve competence and LV deformation analysis in ASO patients.
Databáze: OpenAIRE
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