Human Pancreatic Polypeptide in Children and Young Adults
| Autor: | A. Avinoam Kowarski, Aaron Hanukoglu, Stuart A. Chalew |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Aging medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism Clinical Biochemistry Radioimmunoassay Peptide hormone Biology Pancreatic Polypeptide Biochemistry Sex Factors Endocrinology Reference Values Internal medicine medicine Humans Pancreatic polypeptide Young adult Child Pancreatic hormone Body Weight Biochemistry (medical) Infant Newborn Infant General Medicine Middle Aged Child Preschool Female Gastrointestinal function Body mass index Hormone |
| Zdroj: | Hormone and Metabolic Research. 22:41-43 |
| ISSN: | 1439-4286 0018-5043 |
| Popis: | Measurement of human pancreatic polypeptide may be useful for assessment of gastrointestinal function, integrity of the parasympathetic nervous system or screening for endocrine neoplasia. In adults hPP levels have been reported to increase with age. However hPP levels throughout childhood have not been well characterized in comparison with the adult range. We studied fasting human pancreatic polypeptide (hPP) from 45 pediatric patients, from infancy - 15 years, and 18 older adolescents and adults aged 16-45 years. The mean hPP level of children (233 +/- 147 pg/ml) was significantly higher than that (113 +/- 35 pg/ml) of adults (P less than .0001). There was no difference in mean hPP levels of children with normal growth hormone secretion compared to growth hormone deficient patients. There was no effect of gender or body mass index on hPP levels. We conclude that fasting hPP levels must be interpreted with respect to the age of the subject, children particularly, in that preteens may have higher fasting levels than older teenagers and adults. |
| Databáze: | OpenAIRE |
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