The Analgesic Efficacy of Patient-Controlled Ropivacaine Instillation After Cesarean Delivery
| Autor: | Brian Fredman, Arie Shapiro, Narinder Rawal, Ella Feldman, Robert Jedeikin, Edna Zohar, Shy Shorer |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
medicine.medical_specialty medicine.drug_class Analgesic Double-Blind Method Pregnancy medicine Humans Ropivacaine Prospective Studies Anesthetics Local Pain Postoperative Cesarean Section Local anesthetic business.industry Analgesia Patient-Controlled Surgical wound Amides Surgery Catheter Continuous wound infiltration Anesthesiology and Pain Medicine Anesthesia Morphine Female business Perfusion medicine.drug |
| Zdroj: | Anesthesia & Analgesia. 91:1436-1440 |
| ISSN: | 0003-2999 |
| DOI: | 10.1097/00000539-200012000-00025 |
| Popis: | To assess the efficacy and safety of wound instillation of ropivacaine, when administered via a patient-controlled elastometric pump, 50 term parturients undergoing cesarean delivery were enrolled into this prospective, placebo-controlled, double-blinded study. In all cases, a standard spinal anesthetic was administered. After the surgery, a multihole 20-gauge epidural catheter (B. Braun, Melsungen, Germany) was placed above the fascia such that the tip was sited at the point that demarcated 50% of the length of the surgical wound. Thereafter, the catheter was connected to the elastometric pump. According to a computer-generated randomization schedule, the pump was filled with either ropivacaine 0.2% (Ropivacaine Group) or an equal volume of sterile water (Control Group). Postoperatively, patient-controlled analgesia was administered via the elastometric pump. During the first 6 postoperative hours, a coinvestigator administered "rescue" morphine (2 mg, IV). Thereafter, "rescue" dipyrone (1 g) was administered on patient request. In a subset of 10 patients, blood ropivacaine levels were assessed. Compared with the Control Group, significantly fewer patients in the Ropivacaine Group received "rescue" morphine (92% vs. 48%, respectively) (P |
| Databáze: | OpenAIRE |
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