Giant cell tumors combined with secondary aneurysmal bone cysts are more likely to develop postoperative recurrence: A retrospective study of 256 cases
| Autor: | Abu Moro, Zengming Xiao, Kun Wang, Yun Liu, Yin-Juan Lai, Haijun Tang, Wen-Yu Feng |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male China medicine.medical_specialty medicine.medical_treatment Bone Neoplasms Kaplan-Meier Estimate 03 medical and health sciences 0302 clinical medicine Epidemiology medicine Humans Postoperative Period Survival rate Survival analysis Proportional Hazards Models Retrospective Studies Giant Cell Tumor of Bone Univariate analysis business.industry Hazard ratio Retrospective cohort study General Medicine Confidence interval Curettage Surgery Bone Cysts Aneurysmal Oncology 030220 oncology & carcinogenesis Regression Analysis Female 030211 gastroenterology & hepatology Neoplasm Recurrence Local business |
| Zdroj: | Journal of Surgical Oncology. 120:359-365 |
| ISSN: | 1096-9098 0022-4790 |
| DOI: | 10.1002/jso.25588 |
| Popis: | PURPOSE The epidemiology and clinicopathology of aneurysmal bone cysts (ABCs) secondary to giant cell tumors of bone (GCTBs) have been well documented in the previous literature. However, reports on whether secondary ABCs could affect the postoperative recurrence of GCTBs are rare. This study analyzed the effects of secondary ABCs and other relevant clinical factors on the postoperative recurrence of GCTBs of the extremities. METHODS We retrospectively analyzed 256 cases of GCTBs of the extremities that were treated surgically at our institution. Among them, there were 60 patients diagnosed with GCTBs combined with secondary ABCs and 196 patients diagnosed with simple GCTBs. Intralesional curettage and tumor resection were performed in 136 and 120 cases, respectively. Univariate analysis, Kaplan-Meier survival analysis, and multivariate regression analysis were used to assess the factors for postoperative recurrence. The follow-up period was at least 24 months. RESULTS The total postoperative recurrence rate was 32%. The recurrence rate in the secondary ABCs group was significantly higher than that in the simple GCTBs group (53.3% vs 25.5%, P |
| Databáze: | OpenAIRE |
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