Clinical experience of positron-emission tomography in infective aortic disease
| Autor: | Yuk Law, Stephen W.K. Cheng, Yiu Che Chan, JS Tsang |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Pulmonary and Respiratory Medicine
Aortic arch Adult Male medicine.medical_specialty Prosthesis-Related Infections Time Factors Databases Factual 030204 cardiovascular system & hematology Aortography 030218 nuclear medicine & medical imaging 03 medical and health sciences Aortic aneurysm Blood Vessel Prosthesis Implantation 0302 clinical medicine Aneurysm Blood vessel prosthesis Fluorodeoxyglucose F18 Predictive Value of Tests medicine.artery Positron Emission Tomography Computed Tomography medicine Humans Device Removal Aged Retrospective Studies Aged 80 and over Aorta medicine.diagnostic_test business.industry General Medicine Mycotic aneurysm Middle Aged medicine.disease Anti-Bacterial Agents Aortic Aneurysm Blood Vessel Prosthesis Treatment Outcome Positron emission tomography Surgery Female Tomography Radiology Radiopharmaceuticals Cardiology and Cardiovascular Medicine business Aneurysm Infected |
| Zdroj: | Asian cardiovascularthoracic annals. 26(1) |
| ISSN: | 1816-5370 |
| Popis: | Background Fluorine-18-fluorodeoxyglucose positron-emission tomography with computed tomography has revolutionized medical diagnosis by adding functional activity to anatomic imaging. We report our experience with this technique in patients with mycotic aortic pathology and aortic vascular graft infection. Methods We conducted a retrospective review of a prospective database of patients who underwent 18F-fluorodeoxyglucose positron-emission tomography with computed tomography for suspected infective aortic disease. From 2012 to 2016, 13 patients underwent 18F-fluorodeoxyglucose positron-emission tomography. Of these, 9 (69%) had a vascular graft infection (5 infrarenal aorta, 1 para-visceral, 2 descending, and 1 arch; 2 had previous open surgery and 7 had endovascular interventions) and 4 (31%) had a mycotic aneurysm (2 aortic arch, 1 infrarenal aorta, and 1 distal aorta and common iliac; 3 had endografts). The indications for imaging, location of pathology, 18F uptake, and clinical outcomes were analyzed. Results Eight (62%) patients had a single scan and 5 (38%) had serial scans performed. Among the 5 patients who had serial imaging, 3 showed decreased 18F uptake and 2 had increased uptake. Only one patient underwent subsequent endograft removal; the others were treated with lifelong antibiotics. There were 5 (38%) deaths on follow-up. Conclusion 18F-fluorodeoxyglucose positron-emission tomography with computed tomography could be a valuable adjunct in the diagnosis and surveillance of patients with aortic infection. Serial scans may be useful for monitoring disease activity and response to antibiotic therapy. |
| Databáze: | OpenAIRE |
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