Experimental Reproduction of Stages of the Respiratory Distress Syndrome
Autor: | N. V. Isakova, N. N. Tsybikov, E. V. Prutkina, A. V. Sepp |
---|---|
Rok vydání: | 2013 |
Předmět: |
Cell Extracts
Male Respiratory Distress Syndrome Respiratory distress Neutrophils business.industry media_common.quotation_subject Physiology General Medicine Acute respiratory distress General Biochemistry Genetics and Molecular Biology Rats Disease Models Animal Animals Outbred Strains Animals Humans Medicine Pulmonary Injury Reproduction business Lung Capillary membrane media_common |
Zdroj: | Bulletin of Experimental Biology and Medicine. 155:817-820 |
ISSN: | 1573-8221 0007-4888 |
Popis: | The authors present a method for experimental reproduction of stages of the acute respiratory distress syndrome development, including the initial stage - acute pulmonary injury. Concentrated neutrophil transmitters served as the factor triggering the development of the process. The adequacy of the model was confirmed by the clear-cut morphological stages of the process. The possibility of reproducing the syndrome by injection of concentrated neutrophil transmitters confirmed their leading role in impairment of the alveolar capillary membrane. |
Databáze: | OpenAIRE |
Externí odkaz: |