Liver resection for metastases not of colorectal, neuroendocrine, sarcomatous, or ovarian (NCNSO) origin: A multicentric study
| Autor: | Gilles Mentha, Myron Schwartz, Erik Schadde, Ismail Labgaa, Ksenija Slankamenac, Pierre-Alain Clavien, Kutaiba Alshebeeb, Ghalib Jibara |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Oncology medicine.medical_specialty medicine.medical_treatment Breast Neoplasms Adenocarcinoma 030230 surgery Neuroendocrine tumors 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Carcinoma Hepatectomy Humans Melanoma Survival analysis Aged Gastrointestinal Neoplasms Retrospective Studies Aged 80 and over Ovarian Neoplasms business.industry Liver Neoplasms Sarcoma Retrospective cohort study General Medicine Middle Aged medicine.disease Survival Analysis Neuroendocrine Tumors Treatment Outcome 030220 oncology & carcinogenesis Carcinoma Squamous Cell Female Surgery Neoplasm Recurrence Local Colorectal Neoplasms business Follow-Up Studies |
| Zdroj: | The American Journal of Surgery. 215:125-130 |
| ISSN: | 0002-9610 |
| DOI: | 10.1016/j.amjsurg.2017.09.030 |
| Popis: | Background Liver resection is a well-established treatment for colorectal, neuroendocrine and sarcomatous metastases but remains ill-defined for metastases from other primary sites. This study aimed to analyze the outcomes of hepatic resection for metastases not of colorectal, neuroendocrine, sarcomatous, or ovarian (NCNSO) origin and to identify predictors of outcome. Methods Retrospective analysis of patients undergoing resection for NCNSO metastases in three western centers. Patients were analyzed according to the primary cancer. Outcomes were recurrence and survival. Results We analyzed 188 patients, divided in: gastrointestinal (59), breast (59) and “others” (70). Median time to recurrence was 15.3 months, while median survival was 52 months. Survival at 1, 3, and 5 years was 78%, 60.4% and 47.8%, respectively. In term of prognostic factors, metastases >35 mm from gastrointestinal tumors were associated with lower survival (p = 0.029) and age>60 years was associated with better survival in breast metastases (p = 0.018). Conclusions Liver resection for NCNSO metastases is feasible and results in long-term survival are similar to colorectal metastases. In gastrointestinal metastases, size ( |
| Databáze: | OpenAIRE |
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