The Multi-center Evaluation of the Accuracy of the Contrast MEdium INduced Pd/Pa RaTiO in Predicting FFR (MEMENTOFFR) Study
| Autor: | Antonio Maria Leone, Mariana Faustino, Luís Raposo, José M. de la Torre Hernández, Giuseppe Zimbardo, Eloisa Basile, Cristina Aurigemma, Francesco Burzotta, Giampaolo Niccoli, Antonio Giuseppe Rebuzzi, Nicolas Amabile, Vincent Spagnoli, Ramón López Palop, Sérgio Bravo Baptista, Filippo Crea, Pedro Farto e Abreu, Miren Telleria Arrieta, Italo Porto, Juan Antonio Franco Pelaez, Michel S. Slama, Carlo Trani, Pio Cialdella, Ignacio J. Amat Santos, Roberto Martín-Reyes |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
contrast mediuminduced Pd/Pa Contrast Media CFFR Coronary stenosis Fractional flow reserve 030204 cardiovascular system & hematology contrast FFR FFR 03 medical and health sciences Hyperaemia 0302 clinical medicine medicine Humans cFFR Contrast FFR Contrast mediuminduced Pd/Pa ratio Cardiology and Cardiovascular Medicine 030212 general & internal medicine fractional flow reserve Aged Retrospective Studies contrast medium-induced Pd/Pa ration business.industry Contrast media Curve analysis Coronary Stenosis Limiting rati Middle Aged Hybrid approach Fractional Flow Reserve Myocardial Contrast medium Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE Functional significance Female cFFR contrast FFR contrast mediuminduced Pd/Pa rati FFR fractional flow reserve medicine.symptom business Nuclear medicine |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação instacron:RCAAP EuroIntervention r-FISABIO. Repositorio Institucional de Producción Científica instname r-FISABIO: Repositorio Institucional de Producción Científica Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO) |
| ISSN: | 1774-024X |
| Popis: | AIMS: Adenosine administration is needed for the achievement of maximal hyperaemia fractional flow reserve (FFR) assessment. The objective was to test the accuracy of Pd/Pa ratio registered during submaximal hyperaemia induced by non-ionic contrast medium (contrast FFR [cFFR]) in predicting FFR and comparing it to the performance of resting Pd/Pa in a collaborative registry of 926 patients enrolled in 10 hospitals from four European countries (Italy, Spain, France and Portugal). METHODS AND RESULTS: Resting Pd/Pa, cFFR and FFR were measured in 1,026 coronary stenoses functionally evaluated using commercially available pressure wires. cFFR was obtained after intracoronary injection of contrast medium, while FFR was measured after administration of adenosine. Resting Pd/Pa and cFFR were significantly higher than FFR (0.93±0.05 vs. 0.87±0.08 vs. 0.84±0.08, p |
| Databáze: | OpenAIRE |
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