Chlorhexidine: An Elixir for Periodontics
Autor: | Ramesh Periannan Kathirvelu, Arthiie Thangavelu, Rajasekar Sundram, Soundarya Srinivasan, Sahaya Stelin Kaspar, Bhuvaneshwari Srinivasan |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Lysis
medicine.drug_class lcsh:Analytical chemistry lcsh:RS1-441 Bioengineering Review Article General Biochemistry Genetics and Molecular Biology Bacterial cell structure Microbiology lcsh:Pharmacy and materia medica 03 medical and health sciences Bisbiguanide chemistry.chemical_compound 0302 clinical medicine mouthrinse Antiseptic chemical plaque control medicine 030212 general & internal medicine General Pharmacology Toxicology and Pharmaceutics lcsh:QD71-142 biology business.industry Chlorhexidine chlorhexidine 030206 dentistry biology.organism_classification Mechanism of action chemistry medicine.symptom Antibacterial activity business Bacteria periodontal diseases medicine.drug |
Zdroj: | Journal of Pharmacy & Bioallied Sciences Journal of Pharmacy and Bioallied Sciences, Vol 12, Iss 5, Pp 57-59 (2020) |
ISSN: | 0975-7406 0976-4879 |
Popis: | Chlorhexidine is a cationic bisbiguanide with broad antibacterial activity, and wide spectrum of activity encompassing gram-positive and gram-negative bacteria, yeasts, dermatophytes and some lipophilic viruses. Its antibacterial action is due to the disruption of the bacterial cell membrane by the chlorhexidine molecules, increasing the permeability and resulting in cell lysis. Thus, chlorhexidine plays a key role in the dentistry and is used to treat or prevent periodontal disease, and has earned its eponym of the gold standard. This article reviews in detail about the mechanism of action, indications, forms and various studies related to chlorhexidine. |
Databáze: | OpenAIRE |
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