Association Between Preoperative Chemotherapy and Postoperative Complications in Patients Undergoing Surgery for Ovarian Cancer
| Autor: | David W. Doo, Kian Behbakht, Saketh R. Guntupalli, Jeanelle Sheeder, Susan A. Davidson, Michael S. Guy |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Blood transfusion medicine.medical_treatment Ovariectomy Hematocrit Preoperative care Risk Assessment 03 medical and health sciences 0302 clinical medicine Postoperative Complications Surgical oncology White blood cell Antineoplastic Combined Chemotherapy Protocols Preoperative Care medicine Humans Neoplasm Invasiveness Neoplasm Staging Ovarian Neoplasms Chemotherapy 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Odds ratio Length of Stay Middle Aged medicine.disease Prognosis Combined Modality Therapy Quality Improvement Surgery medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Female Morbidity Ovarian cancer business Follow-Up Studies |
| Zdroj: | Annals of surgical oncology. 23(3) |
| ISSN: | 1534-4681 |
| Popis: | This study sought to determine the association between preoperative chemotherapy and postoperative morbidity and mortality in ovarian cancer patients. The American College of Surgeons National Surgical Quality Improvement Program was used to identify women who underwent surgery for ovarian cancer between 2005 and 2012. The women were divided into two groups based on whether they had received chemotherapy within 30 days before surgery or not. Preoperative variables, intraoperative measures, and postoperative morbidity and mortality were compared using χ 2 and Student’s t test. Multivariable analyses using logistic regression modeling were used to correct for potential confounding variables. Of 1807 patients, 1612 (89.2 %) underwent primary surgery, and 195 (10.8 %) received preoperative chemotherapy. The chemotherapy group had a lower preoperative platelet count (317,640 vs 249,740 plt/μL; P |
| Databáze: | OpenAIRE |
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