Post-Treated Prostate Cancer: Normal Findings and Signs of Local Relapse on Multiparametric Magnetic Resonance Imaging
Autor: | Rui Mateus Marques, João Lopes Dias, Nuno Vasco Costa, João Magalhães Pina, Rita Lucas, Tiago Bilhim, Cecília Leal, Raquel João, Luís Campos Pinheiro |
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Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: |
Male
medicine.medical_specialty Pathology Antineoplastic Agents Hormonal Antineoplastic Agents Hormonal/therapeutic use Urology medicine.medical_treatment Brachytherapy Cryosurgery Neoplasm Recurrence Local/diagnosis Prostate cancer Prostatic Neoplasms/therapy Medicine Humans Radiology Nuclear Medicine and imaging External beam radiotherapy Multiparametric Magnetic Resonance Imaging Prostatectomy Prostatic Neoplasms/diagnosis Radiological and Ultrasound Technology medicine.diagnostic_test Radiotherapy business.industry HSJ IMA HSAC IMA Gastroenterology Prostatic Neoplasms Magnetic resonance imaging Androgen Antagonists General Medicine medicine.disease Magnetic Resonance Imaging Radiation therapy HSM IMA Radiology Neoplasm Recurrence Local business Androgen Antagonists/therapeutic use HSJ URO |
Zdroj: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação instacron:RCAAP |
Popis: | The use of multiparametric magnetic resonance imaging (mp-MRI) for prostate cancer has increased over recent years, mainly for detection, staging, and active surveillance. However, suspicion of recurrence in the set of biochemical failure is becoming a significant reason for clinicians to request mp-MRI. Radiologists should be able to recognize the normal post-treatment MRI findings. Fibrosis and atrophic remnant seminal vesicles after prostatectomy are often found and must be differentiated from local relapse. Moreover, brachytherapy, external beam radiotherapy, cryosurgery, and hormonal therapy tend to diffusely decrease the signal intensity of the peripheral zone on T2-weighted images (T2WI) due to the loss of water content, consequently mimicking tumor and hemorrhage. The combination of T2WI and functional studies like diffusion-weighted imaging and dynamic contrast-enhanced improves the identification of local relapse. Tumor recurrence tends to restrict on diffusion images and avidly enhances after contrast administration either within or outside the gland. The authors provide a pictorial review of the normal findings and the signs of local tumor relapse after radical prostatectomy, external beam radiotherapy, brachytherapy, cryosurgery, and hormonal therapy. |
Databáze: | OpenAIRE |
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