Post-Treated Prostate Cancer: Normal Findings and Signs of Local Relapse on Multiparametric Magnetic Resonance Imaging

Autor: Rui Mateus Marques, João Lopes Dias, Nuno Vasco Costa, João Magalhães Pina, Rita Lucas, Tiago Bilhim, Cecília Leal, Raquel João, Luís Campos Pinheiro
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Male
medicine.medical_specialty
Pathology
Antineoplastic Agents
Hormonal

Antineoplastic Agents
Hormonal/therapeutic use

Urology
medicine.medical_treatment
Brachytherapy
Cryosurgery
Neoplasm Recurrence
Local/diagnosis

Prostate cancer
Prostatic Neoplasms/therapy
Medicine
Humans
Radiology
Nuclear Medicine and imaging

External beam radiotherapy
Multiparametric Magnetic Resonance Imaging
Prostatectomy
Prostatic Neoplasms/diagnosis
Radiological and Ultrasound Technology
medicine.diagnostic_test
Radiotherapy
business.industry
HSJ IMA
HSAC IMA
Gastroenterology
Prostatic Neoplasms
Magnetic resonance imaging
Androgen Antagonists
General Medicine
medicine.disease
Magnetic Resonance Imaging
Radiation therapy
HSM IMA
Radiology
Neoplasm Recurrence
Local

business
Androgen Antagonists/therapeutic use
HSJ URO
Zdroj: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Popis: The use of multiparametric magnetic resonance imaging (mp-MRI) for prostate cancer has increased over recent years, mainly for detection, staging, and active surveillance. However, suspicion of recurrence in the set of biochemical failure is becoming a significant reason for clinicians to request mp-MRI. Radiologists should be able to recognize the normal post-treatment MRI findings. Fibrosis and atrophic remnant seminal vesicles after prostatectomy are often found and must be differentiated from local relapse. Moreover, brachytherapy, external beam radiotherapy, cryosurgery, and hormonal therapy tend to diffusely decrease the signal intensity of the peripheral zone on T2-weighted images (T2WI) due to the loss of water content, consequently mimicking tumor and hemorrhage. The combination of T2WI and functional studies like diffusion-weighted imaging and dynamic contrast-enhanced improves the identification of local relapse. Tumor recurrence tends to restrict on diffusion images and avidly enhances after contrast administration either within or outside the gland. The authors provide a pictorial review of the normal findings and the signs of local tumor relapse after radical prostatectomy, external beam radiotherapy, brachytherapy, cryosurgery, and hormonal therapy.
Databáze: OpenAIRE