New method for viewing Krehbiel flow by polymethylmethacrylate particles suspended in fluorescein solution

Autor:	Yasuaki Yamamoto, Yuichi Ohashi, Tomoyuki Kamao, Yuri Sakane, Yasushi Inoue, Atsushi Shiraishi, Masahiko Yamaguchi, Kiyohiko Ohta, Xiaodong Zheng
Rok vydání:	2014
Předmět:	Adult Male Aging medicine.medical_specialty Materials science Video Recording Meniscus (anatomy) Fluorophotometry Lacrimal punctum Young Adult chemistry.chemical_compound Suspensions Ophthalmology medicine Humans Polymethyl Methacrylate Fluorescein Aged Fluorescent Dyes Blinking Significant difference Lacrimal Apparatus Reproducibility of Results General Medicine Middle Aged University hospital Microspheres Middle age Surgery medicine.anatomical_structure Tear meniscus chemistry Tears Female
Zdroj:	Acta Ophthalmologica. 92:e676-e680
ISSN:	1755-375X
DOI:	10.1111/aos.12444
Popis:	Purpose To investigate the changes in the tear flow velocities caused by ageing. Methods Ninety-nine subjects (41 men, mean age 48.3 ± 20.7 years) were recruited from the Department of Ophthalmology of the Ehime University Hospital. None of the subjects had serious abnormalities of the external surface of the eye. The Krehbiel flow of tears was determined by 40-μm polymethylmethacrylate (PMMA) beads suspended in a fluorescein sodium solution (PPF). The movement of the beads was video recorded through a slit-lamp during normal blinking. The flow of the beads was determined with a Motion analyzer®software (KEYENCE Co., Osaka, Japan). The velocity of the beads in young age, 20–40 years, middle age, 41–60 years and old age, ≥61 years, groups was determined. Results The equation describing the velocity (mm/second) of the PMMA particles as a function of age in the lower tear meniscus measured in the direction of the lacrimal punctum was Y = 2.49−0.04X, where Y = velocity and X = age (r2 = 0.214; p
Databáze:	OpenAIRE
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