A rapid protocol to evaluate coronary flow reserve with myocardial scintigraphy: A prospective study using Regadenoson
| Autor: | F. Debordeaux, H. Douard, Thierry Couffinhal, L. Bordenave, Jean-Baptiste Pinaquy, Q. Ceyrat |
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| Přispěvatelé: | Institut de Neurosciences cognitives et intégratives d'Aquitaine (INCIA), Université Bordeaux Segalen - Bordeaux 2-Université Sciences et Technologies - Bordeaux 1-SFR Bordeaux Neurosciences-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Reproducibility
Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Image quality [SDV]Life Sciences [q-bio] Biophysics Coronary flow reserve Perfusion scanning Blood flow 030218 nuclear medicine & medical imaging Regadenoson 03 medical and health sciences 0302 clinical medicine medicine Clinical endpoint Radiology Nuclear Medicine and imaging Nuclear medicine business Emission computed tomography circulatory and respiratory physiology medicine.drug |
| Zdroj: | Médecine Nucléaire Médecine Nucléaire, Elsevier/Masson, 2020, 44, pp.336-345. ⟨10.1016/j.mednuc.2020.05.001⟩ |
| ISSN: | 0928-1258 |
| DOI: | 10.1016/j.mednuc.2020.05.001⟩ |
| Popis: | Cardiac positron emission tomography (PET) is superior to single-photon emission computed tomography (SPECT) thanks to its quantitative analysis capabilities, especially for measuring myocardial blood flow (MBF) and myocardial flow reserve (MFR). The recent development of new cadmium zinc telluride (CZT) gamma cameras has enabled dynamic acquisition, allowing measurement of MBF and MFR. This prospective study aimed to determine the fastest protocol, to analyse MBF and perfusion imaging. Methods and results From February to June 2018, 10 patients were referred to our centre and prospectively enrolled in our study to evaluate the MBF and MFR, with 5 different reconstruction list-mod. The primary endpoint was to assess the reproducibility of the different reconstruction, and time of acquisition. The secondary endpoint was the evaluation of the image quality of the MPI. The 6-min tests highlighted no significant difference in the flow measurement and MFR (P = 0,15). Differences become significant by decreasing acquisition time. The image quality did not differ significantly (P = 0.6). Conclusion We determined a fast (12mn acquisition) reliable and reproducible protocol to evaluate MBF and MFR without any loss of MPI information. |
| Databáze: | OpenAIRE |
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