Changes in Muscle Cytoarchitecture after Peripheral Nerve Injury and Repair
Autor: | Kristmundsdottir F, Gilmour J, A. J. Carter, M. A. Glasby |
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Rok vydání: | 1998 |
Předmět: |
Male
0301 basic medicine Pathology medicine.medical_specialty Rats Sprague-Dawley 03 medical and health sciences Nerve Fibers Qualitative analysis Peripheral Nerve Injuries Peripheral nerve medicine Animals Peripheral Nerves Muscle fibre Muscle Skeletal skin and connective tissue diseases Transplantation 030102 biochemistry & molecular biology business.industry Injury and repair Anatomy medicine.disease Cell loss Rats 030104 developmental biology Cytoarchitecture Peripheral nerve injury Crush injury Surgery sense organs business |
Zdroj: | Journal of Hand Surgery. 23:365-369 |
ISSN: | 0266-7681 |
Popis: | The aim of this study was to assess the changes which occurred in the rat in target muscles after the injury and repair of a specific peripheral nerve, using several clinically-appropriate surgical techniques. There were alterations in the size, shape, morphology and cytochemical architecture of the fibres of the target muscles. These changes were marked when transection and repair of the nerve was compared with the less-severe crush injury. The method of repair did not correlate significantly with the occurrence of changes in muscle cytoarchitecture. The results suggest that the extent of cell loss and the changes in muscle fibre architecture were influenced by the type of injury, rather than by the method of repair. |
Databáze: | OpenAIRE |
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