Prognostic implications of mean nuclear diameter in breast cancer
| Autor: | L J van Bogaert, H Maisin, C de Muylder, P. Maldague |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Adult
Oncology Cancer Research medicine.medical_specialty Lymphatic metastasis Early Recurrence Breast Neoplasms Disease Breast cancer Text mining Internal medicine medicine Humans Neoplasm Metastasis Aged Cell Nucleus business.industry Mortality rate Middle Aged Prognosis medicine.disease Axilla Tissue sections medicine.anatomical_structure Lymphatic Metastasis Neoplasm Recurrence Local business Research Article |
| Zdroj: | British Journal of Cancer |
| ISSN: | 1532-1827 0007-0920 |
| DOI: | 10.1038/bjc.1980.277 |
| Popis: | The mean nuclear diameter of 100 breast cancers was measured on tissue sections, to evaluate its importance for early prognosis. The cases were subdivided into 3 subgroups: small (25.5% of cases), medium (63.3%) and large (11.2%) nuclei. Early recurrence and mortality rates were investigated in each of the categories. Increasing nuclear size was shown to be related to mortality from metastatic disease. However, large-nucleus tumours had an inverse relationship with lymphnode involvement and possibly with recurrence rate. Hence, in our material nuclear size as a sole criterion was not a good indicator of the early behaviour of operable breast cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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