The prevalence of hypovitaminosis D and secondary hyperparathyroidism in obese Black Americans
| Autor: | Pamela Slaughter, Blakeley I. Denkinger, Nancy G. Sebring, Jack A. Yanovski, Theresa McHugh, Lisa B. Yanoff, Amanda Spitalnik, Shamik J. Parikh, Alan T. Remaley |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Endocrinology Diabetes and Metabolism Parathyroid hormone Article White People vitamin D deficiency Endocrinology Internal medicine Prevalence medicine Vitamin D and neurology Humans Obesity Vitamin D Aged Hyperparathyroidism business.industry Odds ratio Middle Aged Vitamin D Deficiency medicine.disease Diet Records Black or African American Cross-Sectional Studies Logistic Models Female Hyperparathyroidism Secondary Secondary hyperparathyroidism business Body mass index |
| Zdroj: | Clinical Endocrinology. 64:523-529 |
| ISSN: | 1365-2265 0300-0664 |
| Popis: | Summary Context Both obesity (body mass index, BMI ≥ 30 kg/m2) and Black race are associated with a higher risk of vitamin D deficiency and secondary hyperparathyroidism. We hypothesized the risk of hypovitaminosis D would therefore be extraordinarily high in obese Black adults. Objective To study the effects of race and adiposity on 25-hydroxyvitamin D [25(OH)D] and parathyroid hormone (iPTH). Design, Setting and Participants Cross-sectional study of 379 Black and White adults from the Washington D.C. area. BMI ranged from 19·9 to 58·2 kg/m2. Main Outcome Measures Prevalence of hypovitaminosis D [25(OH)D 4·2 pmol/l]. Results Obese Black subjects had lower mean 25(OH)D, 40·3 (SD, 20·3) nmol/l, compared with obese Whites, 64·5 (29·7), P |
| Databáze: | OpenAIRE |
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