Predicting Survival in Potentially Curable Lung Cancer Patients
| Autor: | Linda D. Sharples, Francis C. Wells, Thida Win, Andrew J. Ritchie, Ashley M. Groves, Clare M. Laroche |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Lung Neoplasms Nutritional Status Kaplan-Meier Estimate Disease Predictive Value of Tests Carcinoma Non-Small-Cell Lung Internal medicine Diabetes Mellitus medicine Humans Prospective Studies Lung cancer Survival rate Survival analysis Aged Aged 80 and over Lung cancer surgery Performance status business.industry Body Weight Smoking Middle Aged Prognosis medicine.disease Comorbidity Surgery Physical Fitness Multivariate Analysis Quality of Life Female business Body mass index |
| Zdroj: | Lung. 186:97-102 |
| ISSN: | 1432-1750 0341-2040 |
| DOI: | 10.1007/s00408-007-9067-1 |
| Popis: | Lung cancer is the most common cause of cancer death with unchanged mortality for 50 years. Only localized nonsmall-cell lung cancer (NSCLC) is curable. In these patients it is essential to accurately predict survival to help identify those that will benefit from treatment and those at risk of relapse. Despite needing this clinical information, prospective data are lacking. We therefore prospectively identified prognostic factors in patients with potentially curable lung cancer. Over 2 years, 110 consecutive patients with confirmed localized NSCLC (stages 1–3A) were recruited from a single tertiary center. Prognostic factors investigated included age, gender, body mass index (BMI), performance status, comorbidity, disease stage, quality of life, and respiratory physiology. Patients were followed up for 3-5 years and mortality recorded. The data were analyzed using survival analysis methods. Twenty-eight patients died within 1 year, 15 patients died within 2 years, and 11 patients died within 3 years postsurgery. Kaplan-Meier survival estimates show a survival rate of 51% at 3 years. Factors significantly (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink