Amiodarone-Induced Acute Liver Injury
| Autor: | Anuraj Sudhakaran, Asif Mehmood, Sajeer Bhura, Rajesh Essrani, Shri Jai Kirshan Ravi, Muhammad Rajib Hossain, Shehriyar Mehershahi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Nausea Single Case Amiodarone Shortness of breath Gastroenterology 03 medical and health sciences chemistry.chemical_compound Elevated bilirubin 0302 clinical medicine Internal medicine Lactate dehydrogenase Injection site Acute liver injury medicine lcsh:RC799-869 business.industry Intravenous amiodarone Atrial fibrillation medicine.disease chemistry 030220 oncology & carcinogenesis lcsh:Diseases of the digestive system. Gastroenterology 030211 gastroenterology & hepatology medicine.symptom business Acute hepatitis medicine.drug |
| Zdroj: | Case Reports in Gastroenterology Case Reports in Gastroenterology, Vol 14, Iss 1, Pp 87-90 (2020) |
| ISSN: | 1662-0631 |
| DOI: | 10.1159/000506184 |
| Popis: | Amiodarone is a lipophilic structure with a half-life of 25–100 days. Long-term oral amiodarone is associated with photosensitivity, thyroid dysfunction, and pulmonary and hepatic toxicity. Intravenous amiodarone can lead to sweating, heating sensation, nausea, phlebitis at the injection site, and rarely acute hepatitis. This is a compelling case of a 60-year-old male who developed acute liver injury 24–36 h after starting amiodarone. All the possible causes of acute liver injury were ruled out, and his liver enzymes improved after discontinuing amiodarone. |
| Databáze: | OpenAIRE |
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