Multiple regulation of STE2, a mating-type-specific gene of Saccharomyces cerevisiae
| Autor: | A Hartig, J Holly, V L MacKay, G Saari |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1986 |
| Předmět: |
Transcription
Genetic Saccharomyces cerevisiae Genes Fungal Mating Factor Receptors Cell Surface Pheromones Gene product Transcription (biology) Gene Molecular Biology Regulation of gene expression biology Base Sequence Genetic Complementation Test RNA Cell Biology biology.organism_classification Genes Mating Type Fungal Molecular biology Complementation Gene Expression Regulation Conjugation Genetic Peptides Research Article |
| Popis: | The Saccharomyces cerevisiae STE2 gene, which is required for pheromone response and conjugation specifically in mating-type a cells, was cloned by complementation of the ste2 mutation. Transcription of STE2 is repressed by the MAT alpha 2 gene product, so that the 1.4-kilobase STE2 RNA is detected only in a or mat alpha 2 strains, not in alpha or a/alpha cells. However, STE2 RNA levels are also increased by the mating pheromone alpha-factor and decreased in strains bearing mutations in the nonspecific STE4 gene. Regulation of STE2 expression in a cells is therefore achieved by several mechanisms. |
| Databáze: | OpenAIRE |
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