Sufentanil Sublingual Tablet System (SSTS) for the management of postoperative pain after major abdominal and gynecological surgery within an ERAS protocol: an observational study
| Autor: | Stefano Turi, Luigi Beretta, Marilena Marmiere, Francesco Giuseppe Nisi, Gaetano Lombardi, Francesco Deni |
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| Přispěvatelé: | Turi, S., Deni, F., Lombardi, G., Marmiere, M., Nisi, F. G., Beretta, L. |
| Rok vydání: | 2019 |
| Předmět: |
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medicine.medical_treatment SSTS Sufentanil 03 medical and health sciences 0302 clinical medicine Patient satisfaction 030202 anesthesiology Rating scale medicine postoperative ERAS Journal of Pain Research Postoperative Adverse effect Gynecological surgery Original Research lcsh:R5-920 PCA business.industry analgesia Anesthesiology and Pain Medicine Anesthesia Observational study Analgesia medicine.symptom lcsh:Medicine (General) business 030217 neurology & neurosurgery medicine.drug Abdominal surgery |
| Zdroj: | Journal of Pain Research, Vol Volume 12, Pp 2313-2319 (2019) Journal of Pain Research |
| ISSN: | 1178-7090 |
| DOI: | 10.2147/jpr.s214600 |
| Popis: | Stefano Turi, Francesco Deni, Gaetano Lombardi, Marilena Marmiere, Francesco Giuseppe Nisi, Luigi BerettaDipartimento di Anestesia e Rianimazione, Ospedale San Raffaele, Milano, ItalyBackground: The Sufentanil Sublingual Tablet System (SSTS) is a new, pre-programmed, noninvasive, handheld system for patient-controlled analgesia (PCA) which may allow a faster postoperative recovery compared with standard PCA. The efficacy of SSTS in controlling pain after open abdominal surgery has already been documented. However, to our knowledge SSTS has never been investigated in patients undergoing major surgery within an Enhanced Recovery After Surgery (ERAS) protocol.Methods: This observational, retrospective analysis included consecutive patients undergoing elective major abdominal and gynecological surgery. All patients received the SSTS device once they were fully awake and had a good control of pain at the end of the surgery. We analyzed changes in pain intensity according to the numerical rating scale (NRS) throughout the treatment as well as its duration, the number of administrations, and possible related adverse events. Patients were also interviewed to assess their quality of sleep and overall satisfaction with the SSTS device.Results: The study included 308 patients. Compared to the first SSTS administration, pain intensity decreased from a median NRS of 6 to 0 at day 3, for an overall reduction of 79%. Results were already statistically significant at postoperative day 1 (p |
| Databáze: | OpenAIRE |
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