Muscle-fiber conduction velocity and electromyography as diagnostic tools in patients with suspected inflammatory myopathy: a prospective study

Autor: Henk J. ter Laak, Gerald J D Hengstman, Paul J. Blijham, Machiel J. Zwarts, Baziel G.M. van Engelen
Rok vydání: 2004
Předmět:
Adult
Male
medicine.medical_specialty
Pathology
Physiology
Muscle Fibers
Skeletal
Statistics as Topic
Action Potentials
Electromyography
Muscle fiber conduction velocity
Sensitivity and Specificity
Nerve conduction velocity
Inflammatory myopathy
Cellular and Molecular Neuroscience
Predictive Value of Tests
Reference Values
Physiology (medical)
Internal medicine
Biopsy
Medicine
Humans
Prospective Studies
Myopathy
Prospective cohort study
Muscle
Skeletal
Muscle biopsy
medicine.diagnostic_test
Myositis
business.industry
Electrodiagnosis
Biopsy
Needle
Reproducibility of Results
Middle Aged
medicine.disease
Neuromuscular development and genetic disorders [UMCN 3.1]
Electric Stimulation
Tumor microenvironment [UMCN 1.3]
Genetic defects of metabolism [UMCN 5.1]
Cardiology
Female
Neurology (clinical)
medicine.symptom
business
Zdroj: Muscle and Nerve, 29, 46-50
Muscle and Nerve, 29, 1, pp. 46-50
ISSN: 0148-639X
Popis: Contains fulltext : 58650.pdf (Publisher’s version ) (Closed access) Combinations of different techniques can increase the diagnostic yield from neurophysiological examination of muscle. In 25 patients with suspected inflammatory myopathy, we prospectively performed needle electromyography (EMG) and measured muscle-fiber conduction velocity (MFCV) in a single muscle, using a technique with direct muscle-fiber stimulation and recording. Results of MFCV were compared with final diagnosis, EMG, and needle muscle biopsy. Diagnostic accuracy of combined MFCV and EMG studies was 72%, compared to 60% for EMG alone. This improvement was due to a gain in specificity. The MFCV did not prove useful in discriminating inflammatory myopathy from other myopathies. Furthermore, we found a correlation of 92% between variability of MFCV and myopathic changes in muscle biopsy. We conclude that the utility of electrodiagnostic examination can be increased if EMG examination is combined with MFCV studies.
Databáze: OpenAIRE
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