Mammary carcinoma with osteoclast-like giant cells: A study of four cases and a review of literature
| Autor: | June Koizumi, Madeline Vazquez, Ning Cai |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Histology Stromal cell Angiogenesis Biopsy Fine-Needle Osteoclasts Breast Neoplasms Biology Giant Cells Pathology and Forensic Medicine Biopsy medicine Carcinoma Humans medicine.diagnostic_test Carcinoma Ductal Breast Osteoclast-Like Giant Cell General Medicine Middle Aged Ductal carcinoma medicine.disease Giant cell Cribriform Female Stromal Cells |
| Zdroj: | Diagnostic Cytopathology. 33:246-251 |
| ISSN: | 1097-0339 8755-1039 |
| DOI: | 10.1002/dc.20341 |
| Popis: | Mammary carcinoma with osteoclast-like giant cells (OGCs) is an extremely rare tumor. To the best of our knowledge, only 45 cases have been reported in the literature. Here we report four additional cases of this tumor. The fine-needle aspiration cytology was performed in all four cases, showing an abundance of giant cells and mononucleated stromal cells in intimate association with low- or medium-grade malignant epithelial clusters. Histologically, cribriform patterns predominated in three cases. In one case, OGCs were more pronounced in the vicinity of ductal carcinoma in situ accompanied by marked stromal angiogenesis. This study, as well as review of the literature, underlines the characteristic features of this rare histologic type of carcinoma. |
| Databáze: | OpenAIRE |
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