Qualitative histologic evaluation of the tissue reaction to the polyurethane resin (ricinus communis - based biopolymer) implantation assessed by light and scanning electron microscopy
| Autor: | Gustavo Campos Belmonte, Sérgio Augusto Catanzaro-Guimarães, Angela Kinoshita, Renato Savi Carvalho, Tatiana Peixoto Telles de Sousa, Gilberto Orivaldo Chierici |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Bone growth
Materials science Biocompatibility Scanning electron microscope Organic Chemistry Bone healing Bone tissue lcsh:Chemical technology Bone resorption chemistry.chemical_compound medicine.anatomical_structure osteoconduction biocompatibility chemistry Microscopy Bone repair medicine Chemical Engineering (miscellaneous) lcsh:TP1-1185 polyurethane resin Composite material Polyurethane |
| Zdroj: | Polímeros, Vol 23, Iss 4, Pp 462-467 (2013) Polímeros, Volume: 23, Issue: 4, Pages: 462-467, Published: 26 JUL 2013 Polímeros v.23 n.4 2013 Polímeros (São Carlos. Online) Associação Brasileira de Polímeros (ABPol) instacron:ABPO |
| ISSN: | 1678-5169 |
| Popis: | The tissue reaction of bone tissue accessed by light microscopy and scanning electron microscopy (SEM) images after polyurethane resin implantation is presented in this study. Twenty four male rabbits were used, divided into two groups of 12 animals each (experimental group and control group) in which full-thickness cranial defect was surgically created. At 30 and 90 days post operation 6 animals of each group were euthanized and bone samples were removed for analysis. The microscopic results indicated no inflammatory foreign body reaction, a perfect union between the polymer and surgical bone bed surface, lack of bone resorption and presence of a thin layer of osteogenic material covering the polymer surface in contact with the surgical bone bed. The SEM images demonstrate the porosity of the resin, with diameters from 120 to 500 µm. This important feature of this polymer is associated with its osteoconductivity, allowing the bone growth inside it, improving the integration between the material and bone tissue. These results confirm that polyurethane resin derived from Ricinuscommunis is an excellent bone substitute for use in repair surgery for great bone losses. |
| Databáze: | OpenAIRE |
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