18F-FDG for the staging of patients with differentiated thyroid cancer: Comparison of a dual-head coincidence gamma camera with dedicated PET
| Autor: | Wolfgang Burchert, Joachim Kropp, Wolf-Gunter Franke, A. Kühne, J. Bredow, Tiepolt C, R. Hliscs, B. Beuthien-Baumann |
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| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Coincidence law.invention Iodine Radioisotopes Lesion Fluorodeoxyglucose F18 law medicine Humans Gamma Cameras Radiology Nuclear Medicine and imaging Thyroid Neoplasms Thyroid cancer Aged Neoplasm Staging Gamma camera medicine.diagnostic_test business.industry Thyroidectomy Reproducibility of Results General Medicine Middle Aged medicine.disease Positron emission tomography Lymphatic Metastasis Female Radiology Tomography Radiopharmaceuticals medicine.symptom Nuclear medicine business Emission computed tomography Tomography Emission-Computed |
| Zdroj: | Annals of Nuclear Medicine. 14:339-345 |
| ISSN: | 1864-6433 0914-7187 |
| DOI: | 10.1007/bf02988693 |
| Popis: | Coincidence imaging with a dual-head gamma camera may offer a cost-effective alternative to dedicated PET. The aim of this study was to compare the diagnostic accuracy of coincidence imaging and PET in patients with differentiated thyroid cancer. Thirty-one patients were studied after thyroidectomy and radioiodine ablation. They were injected with a single dose of 300 MBq 18F-FDG. Scanning was performed on a dedicated PET system after 1 hr, and on a coincidence gamma camera after 4 hrs. Based on a lesion-by-lesion comparison, coincidence imaging and PET concurred in 69% of 118 lesions. Based on lesion size, concurrence was 96% in lesions larger than 1.5 cm, and 62% in those between 1 and 1.5 cm. Lesions smaller than 1 cm could not be identified with coincidence imaging. Identical staging was obtained with coincidence imaging and PET in 26/31 patients (84%). In four patients FDG accumulating lesions were shown by both the coincidence camera and the dedicated scanner, but not detectable with any other imaging means and were confirmed histologically on surgery. Although a coincidence camera is technically inferior to a dedicated PET scanner, it may provide clinically useful results in situations were a lesion of sufficient size and FDG uptake is to be expected, e.g. when evaluating a known lesion for malignancy. |
| Databáze: | OpenAIRE |
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