Rheumatoid arthritis and bone health
Autor: | Shanze Ashai, Nicholas C. Harvey |
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Rok vydání: | 2020 |
Předmět: |
Male
medicine.medical_specialty Bone density Inflammatory arthritis Population Osteoporosis 030204 cardiovascular system & hematology Systemic inflammation Arthritis Rheumatoid Fractures Bone 03 medical and health sciences 0302 clinical medicine Adrenal Cortex Hormones Bone Density Risk Factors Internal medicine CME: Rheumatology medicine Humans 030212 general & internal medicine education Adverse effect Bone mineral education.field_of_study business.industry General Medicine medicine.disease Rheumatoid arthritis Female medicine.symptom business |
Zdroj: | Clin Med (Lond) |
ISSN: | 1473-4893 1470-2118 |
DOI: | 10.7861/clinmed.20.6.rabh |
Popis: | Rheumatoid arthritis (RA) is an inflammatory arthropathy affecting 1% of the population, with a female predominance. Systemic inflammation is a key component of RA disease; corticosteroids are often required to rapidly control disease activity. Both inflammation and corticosteroids, however, have an adverse effect on bone mineral density, potentially resulting in osteoporosis and an increased risk of fractures. In this article, we describe the link between RA and impaired bone health, together with appropriate strategies to maintain bone density and reduce fracture risk. Key approaches include achieving adequate control of inflammation, minimising corticosteroid use, monitoring bone mineral density and intervening with antiosteoporosis medications when indicated. |
Databáze: | OpenAIRE |
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