Demographics and clinical characteristics of acute traumatic brain injury patients in the different Neuroimaging Radiological Interpretation System (NIRIS) categories
| Autor: | Max Wintermark, Gang Lu, Guangming Zhu, Hui Chen, Ying Li, Bin Jiang, Paymon Rezaii |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Demographics Traumatic brain injury Neuroimaging 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Brain Injuries Traumatic Humans Medicine Radiology Nuclear Medicine and imaging In patient Demography Radiological and Ultrasound Technology business.industry Emergency department medicine.disease Natural history Clinical trial Radiological weapon Emergency medicine Neurology (clinical) Emergency Service Hospital Tomography X-Ray Computed business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Neuroradiology. 48:104-111 |
| ISSN: | 0150-9861 |
| DOI: | 10.1016/j.neurad.2019.07.002 |
| Popis: | To characterize the demographics, clinical and imaging findings, and outcomes of traumatic brain injury (TBI) patients in each of NeuroImaging Radiological Interpretation System (NIRIS) categories.We considered all consecutive patients transported to Stanford Hospital's emergency department by ambulance or helicopter between November 2015 and April 2017. We retained adult patients (18 years old) for whom a trauma alert was triggered and who underwent a non-contrast head computer tomography (CT) because of suspected TBI. We reviewed the non-contrast CT scans in these patients for the NIH TBI common data elements (CDEs). We recorded, then assessed differences in terms of demographics, clinical characteristics, imaging CDEs, and outcomes in patients from the different NIRIS categories.In all, 1152 patients were included in this study. Patients with NIRIS 0 imaging findings were significantly younger than patients in other NIRIS categories (P0.001). Motor vehicle accidents and falls from height were the most common mechanisms of injury across NIRIS categories. GCS scores decreased with increasing NIRIS category imaging findings and were significantly lower in patients with NIRIS 4 imaging findings (P0.001). Significant differences in NIRIS categories were observed for all imaging CDEs (P0.001), in agreement with the definition of the different NIRIS categories. Mortality increased progressively with increasing NIRIS severity.TBI patients in different NIRIS categories have different clinical characteristics, hospital courses and outcomes. This natural history assessment of patients from different NIRIS categories could thus serve as a reference standard for future TBI clinical trials. |
| Databáze: | OpenAIRE |
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