Schistosoma japonicum-infected sentinel mice: Surveillance and spatial point pattern analysis in Hubei province, China, 2010–2018
| Autor: | Guo Li, Lingfeng Dai, Bo Li, Hui Wang, Yanyan Chen, Junjing Yang, Si Liu, Jian-Bing Liu, Xiao-Wei Shan |
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| Rok vydání: | 2020 |
| Předmět: |
Male
0301 basic medicine Microbiology (medical) China Veterinary medicine Ripley's K-function Snails 030106 microbiology Animals Wild Schistosomiasis Point pattern analysis Low transmission Risk Assessment Schistosoma japonicum lcsh:Infectious and parasitic diseases law.invention Mice 03 medical and health sciences 0302 clinical medicine Rivers law medicine Animals Humans lcsh:RC109-216 030212 general & internal medicine Cities Schistosoma Spatial Analysis Point pattern biology General Medicine Spatial clustering biology.organism_classification medicine.disease Infectious Diseases Transmission (mechanics) Sentinel mice surveillance Schistosomiasis japonica Yangtze river Sentinel Surveillance Disease transmission Geographic information system |
| Zdroj: | International Journal of Infectious Diseases, Vol 99, Iss, Pp 179-185 (2020) |
| ISSN: | 1201-9712 |
| Popis: | Objectives: Progress in national schistosomiasis control in China has successfully reduced disease transmission in many districts. However, a low transmission rate hinders conventional snail surveys in identifying areas at risk. In this study, Schistosoma japonicum-infected sentinel mice surveillance was conducted to identify high-risk areas of schistosomiasis transmission in Hubei province, China. Methods: The risk of schistosomiasis transmission was assessed using sentinel mice monitoring in Hubei province from 2010 to 2018. Field detections were undertaken in June and September, and the sentinel mice were kept for approximately 35 days in a laboratory. They were then dissected to determine whether schistosome infection was present. Ripley's K-function and kernel density estimation were applied to analyze the spatial distribution and positive point pattern of schistosomiasis transmission. Results: In total, 190 sentinel mice surveillance sites were selected to detect areas of schistosomiasis infection from 2010 to 2018, with 29 (15.26%) sites showing infected mice. Of 4723 dissected mice, 256 adult worms were detected in 112 infected mice. The infection rate was 2.37%, with an average of 2.28 worms detected per infected mouse. Significantly more infected mice were detected in the June samples than in the September samples (χ2 = 12.11, p |
| Databáze: | OpenAIRE |
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