Effects of chronic metformin treatment on training adaptations in men and women with hyperglycemia: A prospective study

Autor:	Laura Alvarez-Jimenez, Juan Fernando Ortega, Ricardo Mora-Rodríguez, Alfonso Moreno-Cabañas, Felix Alberto Morales Palomo
Rok vydání:	2022
Předmět:	Male Metabolic Syndrome Nutrition and Dietetics Endocrinology Diabetes and Metabolism Medicine (miscellaneous) Middle Aged Metformin Exercise Therapy Endocrinology Hyperglycemia Humans Female Prospective Studies Insulin Resistance
Zdroj:	Obesity. 30:1219-1230
ISSN:	1930-739X 1930-7381
DOI:	10.1002/oby.23410
Popis:	This study aimed to determine whether chronic metformin use interferes with the improvements in insulin resistance (IR) and cardiorespiratory fitness with aerobic training in people with hyperglycemia and metabolic syndrome (MetS).A total of 63 middle-aged (53 [7] years) individuals with MetS and obesity (BMI = 32.8 [4.5] kg/mFasting insulin and HOMA-IR decreased similarly in both groups with training (EXER+MET: -4.3% and -10.6%; EXER: -5.3% and -14.5%; p value for time = 0.005). However, metformin use reduced VOMetformin use was associated with attenuated VO
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dc3d710b310dacd3a2920386281ac2 https://doi.org/10.1002/oby.23410 Zobrazit plný text záznamu Plný text