Low Serum B12 Concentrations Are Associated with Low B12 Dietary Intake But Not with Helicobacter pylori Infection or Abnormal Gastric Function in Rural Mexican Women
| Autor: | Jorge L. Rosado, Lindsay H. Allen, Alex Brito, Carina Sosa, Miriam Aracely Anaya-Loyola, Haydé Vergara-Castañeda |
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| Rok vydání: | 2019 |
| Předmět: |
Helicobacter pylori infection
Physiology 030209 endocrinology & metabolism 03 medical and health sciences 0302 clinical medicine Animal source foods polycyclic compounds Medicine Vitamin B12 Mexico 030505 public health Nutrition and Dietetics Helicobacter pylori biology business.industry Dietary intake gastric function nutritional and metabolic diseases vitamin B12 deficiency Odds ratio biology.organism_classification Dietary Reference Intake biology.protein Antibody diet 0305 other medical science business Food Science |
| Zdroj: | Nutrients Volume 11 Issue 12 |
| ISSN: | 2072-6643 |
| Popis: | Background: Gastric function, Helicobacter pylori infection, and vitamin B12 (B12) dietary intake were assessed as predictors of serum B12. Methods: H. pylori antibodies, gastric function, B12 dietary intake, and biochemical/hematological parameters were measured in 191 adult women from two rural communities in Queré taro, Mexico. Results: The overall mean serum B12 concentration was 211 ± 117 pmol/L. The prevalences of low (&le 148 pmol/L), marginal (148 to 221 pmol/L), and adequate (> 221 pmol/L) serum B12 were 28.4%, 31.1%, and 40.5%, respectively. Seventy-one percent of women tested positive for H. pylori antibodies. The prevalence of gastric function categories did not differ by serum B12 categories. The odds ratio for having low serum B12 was 2.7 (p = 0.01) for women with an intake below the estimated average requirement, 3.6 (p = 0.01) for those in the lowest tertile of total B12 intake, and 3.0 (p = 0.02) for those in the lowest tertile of B12 intake from animal source foods. Age and B12 intake were predictors of serum B12 concentrations [serum B12 (pmol/L) = 90.060 + 5.208 (B12 intake, µ g/day) + 2.989 (age, years). Conclusions: Low serum B12 concentrations were associated with low B12 dietary intake but not with H. pylori infection or abnormal gastric function in rural Mexican women. |
| Databáze: | OpenAIRE |
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