On the use of oxygenic photosynthesis for the sustainable production of commodity chemicals

Autor: Filipe Branco dos Santos, Que Chen, Hugo Pineda Hernández, Klaas J. Hellingwerf, Adam A. Pérez
Přispěvatelé: Molecular Microbial Physiology (SILS, FNWI)
Rok vydání: 2018
Předmět:
Zdroj: Physiologia Plantarum
Physiologia Plantarum, 166(1), 413-427. Wiley-Blackwell
ISSN: 1399-3054
0031-9317
Popis: A sustainable society will have to largely refrain from the use of fossil carbon deposits. In such a regime, renewable electricity can be harvested as a primary source of energy. However, as for the synthesis of carbon-based materials from bulk chemicals, an alternative is required. A sustainable approach towards this is the synthesis of commodity chemicals from CO2 , water and sunlight. Multiple paths to achieve this have been designed and tested in the domains of chemistry and biology. In the latter, the use of both chemotrophic and phototrophic organisms has been advocated. 'Direct conversion' of CO2 and H2O, catalyzed by an oxyphototroph, has excellent prospects to become the most economically competitive of these transformations, because of the relative ease of scale-up of this process. Significantly, for a wide range of energy and commodity products, a proof of principle via engineering of the corresponding production organism has been provided. In the optimization of a cyanobacterial production organism, a wide range of aspects has to be addressed. Of these, here we will put our focus on: (1) optimizing the (carbon) flux to the desired product; (2) increasing the genetic stability of the producing organism, and (3) maximizing its energy conversion efficiency. Significant advances have been made on all these three aspects during the past two years and these will be discussed: (1) increasing the carbon partitioning to > 50%; (2) aligning product formation with the growth of the cells; and (3) expanding the PAR region for oxygenic photosynthesis.
Databáze: OpenAIRE
Externí odkaz: