Impact of geo-imputation on epidemiologic associations in a study of outdoor air pollution and respiratory hospitalization

Autor: Edward F. Fitzgerald, Francis P. Boscoe, Syni-An Hwang, Shao Lin, Rena R. Jones, Danielle N. Medgyesi
Rok vydání: 2019
Předmět:
Zdroj: Spatial and spatio-temporal epidemiology. 32
ISSN: 1877-5853
Popis: Imputation of missing spatial attributes in health records may facilitate linkages to geo-referenced environmental exposures, but few studies have assessed geo-imputation impacts on epidemiologic inference. We imputed patient Census tracts in a case-crossover analysis of fine particulate matter (PM2.5) and respiratory hospitalizations in New York State (2000–2005). We observed non-significantly higher PM2.5 exposures, high accuracy of binary exposure assignment (89 to 99%), and marginally different hazard ratios (HRs) (−0.2 to 0.7%). HR differences were greater in urban versus rural areas. Given its efficiency and nominal influence on accuracy of exposure classification and measures of association, geo-imputation is a candidate method to address missing spatial attributes for health studies.
Databáze: OpenAIRE