Data from Stearoyl Co-A Desaturase 1 as a ccRCC Therapeutic Target: Death by Stress
Autor: | William Y. Kim, Janet Y. Leung |
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Rok vydání: | 2023 |
DOI: | 10.1158/1078-0432.c.6521034.v1 |
Popis: | There is a need for the discovery of novel therapeutic strategies to effectively treat advanced clear cell renal cell carcinoma (ccRCC). Inhibition of stearoyl-coA desaturase 1 (SCD1) in ccRCC reveals antitumor activity, independently and in synergy with mTOR inhibition. SCD1 may be a potential novel therapeutic target in treating ccRCC. Clin Cancer Res; 19(12); 3111–3. ©2013 AACR. |
Databáze: | OpenAIRE |
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