Pediatric subcutaneous panniculitis-like T-cell lymphoma with favorable result by immunosuppressive therapy: a report of two cases

Autor:	Tsuyako Iwai, Asayuki Iwai, Naoko Nakano, Kozo Nagai, Eiichi Ishii, Kouichi Ohshima, Hisamichi Tauchi
Rok vydání:	2014
Předmět:	Male medicine.medical_specialty Pathology Panniculitis medicine.drug_class Antibiotics Lymphoma T-Cell Cohort Studies Subcutaneous Panniculitis-Like T-Cell Lymphoma Risk Factors medicine Humans Child Autoimmune disease Erythema nodosum business.industry Hematology Gene rearrangement medicine.disease Lymphoma Oncology Pediatrics Perinatology and Child Health Histopathology Female business Immunosuppressive Agents
Zdroj:	Pediatric hematology and oncology. 31(6)
ISSN:	1521-0669
Popis:	Subcutaneous panniculitis-like T-cell lymphoma (SPTL) is a rare type of skin lymphoma. Histopathology mimicking a lobular panniculitis makes it difficult to distinguish SPTL from benign autoimmune disease. We present cases of a 10-year-old female and an 11-year-old male with SPTL showing recurrent panniculitis and systemic manifestations. Initially, antibiotics and steroids were administered to treat infectious disease and benign panniculitis. However, they experienced recurrent fever and erythema nodosum. Additional immunohistochemistry and T-cell receptor (TCR) gene rearrangement analyses were performed, enabling the establishment of an SPTL diagnosis. The affected patients were given immunosuppressive therapy with favorable results.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f3da398558109b8f022403b4b68576 https://pubmed.ncbi.nlm.nih.gov/24684413 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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