Clinical profile and 1-year clinical outcomes of super elderly patients admitted with acute heart failure
| Autor: | Gema Miñana, Amparo Villaescusa, Miguel Lorenzo, Raquel Heredia, Clara Sastre, Julio Núñez, Rafael de la Espriella, Adriana Conesa, Eduardo Núñez, Enrique Santas, Jose Civera, Gonzalo Núñez, Anna Mollar, Antoni Bayes-Genis, Clara Bonanad |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty 030204 cardiovascular system & hematology Ventricular Function Left 03 medical and health sciences 0302 clinical medicine Internal medicine Internal Medicine Humans Medicine 030212 general & internal medicine Child Aged Aged 80 and over Heart Failure Ejection fraction business.industry Female sex Stroke Volume Mean age Middle Aged Prognosis medicine.disease Hospitalization Increased risk Heart failure Cohort Female business All cause mortality |
| Zdroj: | European Journal of Internal Medicine. 81:78-82 |
| ISSN: | 0953-6205 |
| DOI: | 10.1016/j.ejim.2020.05.017 |
| Popis: | There is scarce information about the clinical profile and prognosis of acute heart failure (AHF) at the extreme ranges of age. We aimed to evaluate the 1-year death (all-cause mortality and HF-death) and HF-rehospitalizations of patients ≥85 years admitted for AHF.We prospectively evaluated a cohort of 3054 patients admitted with AHF from 2007 to 2018 in a third-level center. Age was categorized per 10-year categories (65 years; 65-74 years, 75-84 years, and ≥85 years). The risk of mortality and HF-rehospitalizations across age categories was evaluated with Cox regression analysis and Cox regression adapted for competing events as appropriate.The mean age was 73.6 ± 11.2 years, 48.9% were female, and 52.8% had preserved left ventricular ejection fraction (HFpEF). A total of 414 (13.6%) patients were ≥85 years. Among this group of age, female sex and HFpEF phenotype were more frequent. At 1-year follow-up 667 all-cause deaths (22,1%), 311 HF-deaths (10.1%) and 693 HF-hospitalizations (22,7%) were recorded. After multivariable adjustment, and compared to patients65 years, a stepwise increased risk of all-cause mortality and HF-death was found for each decade increase in age, especially for patients ≥85 years (HR=3.47; 95% CI: 2.49 - 4.84, p0.001, HR=3.31; 95% CI: 1.95 - 5.63; p0.001, respectively). This subgroup of patients also showed an increased risk of HF-rehospitalization (HR=1.58; 95% CI: 1.16 - 2.16, p=0.004).Super elderly patients admitted with AHF showed a dramatically increased risk of 1-year death. This subset of patients also shown an increased risk of 1-year HF-readmission. |
| Databáze: | OpenAIRE |
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