The Korean Hypertension Cohort study: design and baseline characteristics
| Autor: | Ho Gyun Shin, Ju Hee Lee, Jae Yeong Cho, Kye Hun Kim, Song Hee Cho, Jean Kyung Bak, Kyun Ik Park, Hae Young Lee, Jang Hoon Lee, Gyu Chul Oh, Se Yong Jang, Heesun Lee, Jae Hyeong Park, Kwang-Il Kim, Seung Pyo Lee, Jieun Jang, Hogon Kim, Ju Yeon Lee, Si Hyuck Kang, Sue K. Park |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
business.industry Public health Cardiology Cohort Health resource Disease Blood pressure Cardiovascular Diseases Heart Disease Risk Factors Risk Factors Sample size determination Internal medicine Baseline characteristics Hypertension Republic of Korea medicine Medicine Humans Original Article business Cohort study |
| Zdroj: | The Korean Journal of Internal Medicine The Korean Journal of Internal Medicine, Vol 36, Iss 5, Pp 1115-1125 (2021) |
| ISSN: | 2005-6648 1226-3303 |
| DOI: | 10.3904/kjim.2020.551 |
| Popis: | Background/Aims: Hypertension (HT) has a significant impact on public health and medical expenses. However, HT is a chronic disease that requires the long-term follow-up of a large number of patients.Methods: The Korean Hypertension Cohort (KHC) study aimed to develop a model for calculating cardiovascular risk in HT patients by linking and utilizing the detailed clinical and longitudinal data from hospitals and the national health insurance claim database, respectively. This cohort had a planned sample size of over 11,000 HT patients and 100,000 non-HT controls. Eligible patients were hypertensive patients, who were presenting for the first time and were diagnosed with HT as a main disease from 2006 to 2011. Long-term survival data over a period of approximately 9 years were obtained from the national health insurance claim and national health examination data.Results: This cohort enrolled 11,083 patients with HT. The mean age was 58.87 ± 11.5 years, 50.5% were male, and 31.4% were never-treated HT. Of the enrolled patients, 32.9% and 37.7% belonged to the high and moderate cardiovascular risk groups, respectively. Initial blood pressures were 149.4 ± 18.5/88.5 ± 12.5 mmHg. During the 2 years hospital data follow-up period, blood pressures lowered to 130.8 ± 14.1/78.0 ± 9.7 mmHg with 1.9 ± 1.0 tablet doses of antihypertensive medication. Cardiovascular events occurred in 7.5% of the overall patients; 8.5%, 8.8%, and 4.7% in the high, moderate, and low risk patients, respectively.Conclusions: The KHC study has provided important information on the long-term outcomes of HT patients according to the blood pressure, comorbid diseases, medication, and adherence, as well as health behaviors and health resource use. |
| Databáze: | OpenAIRE |
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