New challenges for management of COVID-19 patients: Analysis of MDCT based 'Automated pneumonia analysis program'
| Autor: | Koray Hekimoglu, Dorina Esendagli, Rahime Sezer, Çiğdem Erol |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pneumonic scoring
COPD medicine.medical_specialty business.industry Automated pneumonia analysis Mortality rate R895-920 Retrospective cohort study macromolecular substances Disease medicine.disease Malignancy Intensive care unit Article law.invention Medical physics. Medical radiology. Nuclear medicine Pneumonia law Heart failure Internal medicine medicine Radiology Nuclear Medicine and imaging COVID-19 pneumonia business |
| Zdroj: | European Journal of Radiology Open, Vol 8, Iss, Pp 100370-(2021) European Journal of Radiology Open |
| ISSN: | 2352-0477 |
| DOI: | 10.1016/j.ejro.2021.100370 |
| Popis: | Highlights • CT pneumonia analysis program is an objective way to determine the disease severity. • The population over the age of 60 and with certain comorbidities such as DM, CHF, and COPD are more prone to severe disease than other patients. • CRP, Neutrophil/Lymphocyte, troponin levels are positive predictors for clinical worsening. Purpose The aim of this study is to define the role of an “Automated Multi Detector Computed Tomography (MDCT) Pneumonia Analysis Program’’ as an early outcome predictor for COVID-19 pneumonia in hospitalized patients. Materials and Methods A total of 96 patients who had RT-PCR proven COVID-19 pneumonia diagnosed by non-contrast enhanced chest MDCT and hospitalized were enrolled in this retrospective study. An automated CT pneumonia analysis program was used for each patient to see the extent of disease. Patients were divided into two clinical subgroups upon their clinical status as good and bad clinical course. Total opacity scores (TOS), intensive care unit (ICU) entry, and mortality rates were measured for each clinical subgroups and also laboratory values were used to compare each subgroup. Results Left lower lobe was the mostly effected side with a percentage of 78.12 % and followed up by right lower lobe with 73.95 %. TOS, ICU entry, and mortality rates were higher in bad clinical course subgroup. TOS values were also higher in patients older than 60 years and in patients with comorbidities including, Hypertension (HT), Diabetes Mellitus (DM), Chronic Obstructive Pulmonary Disease (COPD), Chronic Heart Failure (CHF) and malignancy. Conclusion Automated MDCT analysis programs for pneumonia are fast and an objective way to define the disease extent in COVID-19 pneumonia and it is highly correlated with the disease severity and clinical outcome thus providing physicians with valuable knowledge from the time of diagnosis. |
| Databáze: | OpenAIRE |
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