Plasma therapy: a passive resistance against the deadliest

Autor:	Anita Hansda, Debarati Biswas, Aishwarya Bhatta, Nishant Chakravorty, Gayatri Mukherjee
Rok vydání:	2021
Předmět:	Pharmacology SARS-CoV-2 Immunology Immunization Passive Animals COVID-19 Immunology and Allergy Antibodies Viral Antibodies Neutralizing Pandemics COVID-19 Serotherapy
Zdroj:	Human Vaccines & Immunotherapeutics. 18
ISSN:	2164-554X 2164-5515
DOI:	10.1080/21645515.2021.2006026
Popis:	Convalescent plasma therapy provides a useful therapeutic tool to treat infectious diseases, especially where no specific therapeutic strategies have been identified. The ongoing pandemic puts back the spotlight on this age-old method as a viable treatment option. In this review, we discuss the usage of this therapy in different diseases including COVID-19, and the possible mechanisms of action. The current review also discusses the progress of therapeutic applications of blood-derivatives, from the simple transfer of immunized animal sera, to the more target-specific intravenous administration of human immunoglobulins from a pool of convalescent individuals, in both infectious and non-infectious diseases of various etiologies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154a87e28f559fc3b81ecdb4e5989866 https://doi.org/10.1080/21645515.2021.2006026 Zobrazit plný text záznamu