Using fine-scale spatial genetics of Norway rats to improve control efforts and reduce leptospirosis risk in urban slum environments
| Autor: | Gorete Rodrigues, Jonathan L. Richardson, Christian Hernandez, Albert I. Ko, James M. Shirvell, Federico Costa, James E. Childs, Carol Mariani, Soledad Serrano, Ticiana Carvalho-Pereira, Adalgisa Caccone, Mayara Carvalho, Josh Taylor, Arsinoê C. Pertile, Mary K. Burak, Gabriel Pedra, Jesus A. Panti-May |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0106 biological sciences
0301 basic medicine Population vector control Population genetics Biology 010603 evolutionary biology 01 natural sciences 03 medical and health sciences 11. Sustainability Genetics reservoir host favela education intervention Ecology Evolution Behavior and Systematics Wildlife conservation spatial scale education.field_of_study Bacterial disease Ecology public health population genetics individual‐based sampling landscape genetics Original Articles Genetic divergence urban ecology 030104 developmental biology Urban ecology Spatial ecology Biological dispersal Original Article epidemiology General Agricultural and Biological Sciences |
| Zdroj: | EVOLUTIONARY APPLICATIONS Evolutionary Applications |
| Popis: | The Norway rat (Rattus norvegicus) is a key pest species globally and responsible for seasonal outbreaks of the zoonotic bacterial disease leptospirosis in the tropics. The city of Salvador, Brazil, has seen recent and dramatic increases in human population residing in slums, where conditions foster high rat density and increasing leptospirosis infection rates. Intervention campaigns have been used to drastically reduce rat numbers. In planning these interventions, it is important to define the eradication units ‐ the spatial scale at which rats constitute continuous populations and from where rats are likely recolonizing, post‐intervention. To provide this information, we applied spatial genetic analyses to 706 rats collected across Salvador and genotyped at 16 microsatellite loci. We performed spatially explicit analyses and estimated migration levels to identify distinct genetic units and landscape features associated with genetic divergence at different spatial scales, ranging from valleys within a slum community to city‐wide analyses. Clear genetic breaks exist between rats not only across Salvador but also between valleys of slums separated by |
| Databáze: | OpenAIRE |
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