Fungichromin: A Substance from Streptomyces padanus with Inhibitory Effects on Rhizoctonia solani

Autor: Fen-Lin Hsu, Hsin-Der Shih, Yung-Chuan Liu, J. W. Huang, Rajasekhar Dodda, Vanisree Mulabagal
Rok vydání: 2002
Předmět:
Zdroj: Journal of Agricultural and Food Chemistry. 51:95-99
ISSN: 1520-5118
0021-8561
DOI: 10.1021/jf025879b
Popis: Streptomyces padanus strain PMS-702 is an antagonist of Rhizoctonia solani AG-4, the causal agent of damping-off of cabbage. Treatment of cabbage seeds with the culture filtrate of S. padanus strain PMS-702 was effective in reducing the incidence of damping-off of cabbage. The major active ingredient from the culture filtrate of S. padanus strain PMS-702 was purified by silica gel column chromatography and identified as the polyene macrolide, fungichromin, by NMR and mass spectral data. Bioassay studies showed that fungichromin had a strong antifungal activity against R. solani AG-4, and its minimum inhibitory concentration (over 90% inhibition) was found to be 72 μg/mL. This is the first report of fungichromin from S. padanus as an active ingredient for the control of Rhizoctonia damping-off of cabbage. Keywords: Fungichromin; Streptomyces padanus; Rhizoctonia solani; biocontrol; antifungal substance; polyene macrolide
Databáze: OpenAIRE