Growth Rate of Pseudomonas aeruginosa Biofilms on Slippery Butyl Methacrylate-Co-Ethylene Dimethacrylate (BMA-EDMA), Glass and Polycarbonate Surfaces
| Autor: | Helena Valquier-Flynn, Christopher D Wentworth, Christina L. Wilson, Andrea E. Holmes |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Materials science
Biofilm 030206 dentistry 02 engineering and technology 021001 nanoscience & nanotechnology Antimicrobial resistance Article Contact angle 03 medical and health sciences Surface coating 0302 clinical medicine Chemical engineering visual_art Biofilm growth rate Pseudomonas aeruginosa Surface roughness visual_art.visual_art_medium Shear stress Growth rate Porous polymer surface Polycarbonate 0210 nano-technology Ethylene dimethacrylate |
| Zdroj: | Journal of biotechnology & biomaterials |
| ISSN: | 2155-952X |
| Popis: | Bacterial biofilms pose a significant health risk when they grow on devices placed or implanted in the human body. There is a need to develop new materials that can be used as surface coatings on such devices to inhibit biofilm growth. We report on measurements of the biofilm growth rate on a new polymeric material, slippery BMA-EDMA, which can be used as a surface coating for medical devices. Growth rate measurements are also reported for polycarbonate and glass surfaces, for comparison. Measurements are made in a medium shear stress fluid environment. The physical properties of the surfaces are characterized using contact angle, surface roughness, surface skewness and surface kurtosis. Growth rate on the slippery BMA-EDMA is found to be the smallest of the three surfaces. Growth rate is weakly correlated with surface hydrophobicity and surface roughness, while it is strongly correlated with surface skewness and kurtosis. |
| Databáze: | OpenAIRE |
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